Nasal oxygen may increase the sur­vival rate of cancer patients

Category: Cancer

Nasal oxygen may increase the sur­vival rate of cancer patients

Can nasal oxygen create an “energy crisis” for cancer?

The metabolism or energy producing characteristics of cancer cells are fundamentally different from non-cancerous cells. Cancer cells rely on an anaerobic (low oxygen) metabolism for their energy, that is, they can create ATP (Adenosine-5’-triphosphate) an energy molecule and their cellular fuel best in a low oxygen environment.

This has lead researchers to speculate that increasing oxygen “consumption” in patients may cause cancer energy problems and decrease or stop cancer production.

Nasal Oxygen as cancer treatment

Nasal Oxygen CancerNorth­eastern Uni­ver­sity researchers have found that inhaling sup­ple­mental oxygen—40 to 60 per­cent oxygen as opposed to the 21 per­cent oxygen in air—can weaken immuno­sup­pres­sion and awaken anti-​​tumor cells. This approach, which has been studied for more than three decades, may dra­mat­i­cally increase the sur­vival rate of cancer patients. These finding were recently pub­lished in Sci­ence Trans­la­tional Med­i­cine.

“Breathing sup­ple­mental oxygen opens up the gates of the tumor fortress and wakes up ‘sleepy’ anti-​​​​tumor cells, enabling these sol­diers to enter the fortress and destroy it,” explained Sitkovsky, the Eleanor W. Black Chair and Pro­fessor of Immuno­phys­i­ology and Phar­ma­ceu­tical Biotech­nology at North­eastern and the founding director of the university’s New Eng­land Inflam­ma­tion and Tissue Pro­tec­tion Insti­tute. “How­ever, if anti-​​​​tumor immune cells are not present, oxygen will have no impact.”1

Simply, in a cancer cell environment of low-oxygen, killer cells of the immune system are deprived of the oxygen they need to kill cancer. Getting oxygen into these cancer cells awaken the anti-​​​​tumor cells.

How do you get more oxygen into your cells?  Recent research from Duke University says exercise

From Duke University: One way many cancers grow resistant to treatment is by generating a web of blood vessels that are so jumbled they create an oxygen depleted cellular environment. With oxygen starvation, the tumor gains a sort of cloaking device that protects it from the toxic effects of chemotherapy drugs and radiation, which are designed to seek out well-oxygenated tissue.

In a study published in the Journal of the National Cancer Institute, researchers led by Duke Cancer Institute (DCI) scientists studied the impact of exercise in models of breast cancer in mice. They found that exercise stimulated significant improvements in the number and function of blood vessels around the tumors, improving oxygen flow to the cancer site. When treated with chemotherapy, the tumors shrank markedly better than they did in sedentary animals.2

How do you get more oxygen into your cells? PolyMVA

Another option to exercise to increase oxygen levels in the cancer environment is to introduce PolyMVA both intravenously and orally.

This from the Website

Lipoic Acid Mineral Complex (the complex inside of Poly-MVA) is a redox molecule (this means it can accept electrical charge and donate that charge, which makes it an extremely effective energy-transferring molecule) that facilitates energy charge transfer at the cellular level.

It can safely and effectively protect cells and provide energy to them.

Many years of research and clinical studies provide consistent and ongoing evidence that Poly-MVA can support gene repair (in genes damaged by cancer), various therapies and degeneration because of its mitochondrial up-regulation with increased oxygen. Once inside the cell, Poly-MVA supports normal energy production of ATP via the Krebs cycle and its oxygen pathways. This interferes with the particular energy metabolism of the (anaerobic) cancer cell by targeting the mitochondria which allows for a change in the cell properties.

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1. Leone RD, Horton MR, Powell JD. Something in the air: hyperoxic conditioning of the tumor microenvironment for enhanced immunotherapy. Cancer Cell. 2015 Apr 13;27(4):435-6. doi: 10.1016/j.ccell.2015.03.014.

2. Dewhirst MW Modulation of Murine Breast Tumor Vascularity, Hypoxia, and Chemotherapeutic Response by Exercise JNCI J Natl Cancer Inst (2015) 107 (5): djv040 doi: 10.1093/jnci/djv04