The main factor in stem cell treatment success for knee pain? The experience and knowledge of the doctor.

Category: Blog

Recently, there has been a wave of remarkable studies from some of the world’s leading research institutions showing the effectiveness of using stem cell injections for the treatment of knee osteoarthritis.

In the laboratory and more importantly in clinical observation, doctors are showing that it is possible through the regeneration of damaged bone, cartilage, and the soft tissue of ligaments and tendons to non-surgically biologically repair even the most severely damaged knees. Stem cell therapy has presented itself as a clear and viable option to knee replacement.

Stem Cell Injections are part of our treatment plan for joint injuries and chronic pain. We have specialized, since 1999, in the non-surgical treatment of joint injuries, using techniques such as prolotherapy, platelet-rich plasma therapy, and stem cell therapy to regenerate joint tissue. We have performed tens of thousands of procedures. This experience allows us to take a dual approach to joint injury with the use of stem cells and PRP to treat within the joint, and the use of prolotherapy to strengthen and regenerate the supporting structure of the joint.

Stem Cell Therapy in the hands of an experienced physician

Before we get into some of the research surrounding long-term healing success of stem cell therapy in degenerative knee disease, let’s spend a moment discussing the experience of the doctor giving the treatment. Having seen countless patients who have been treated in other offices with stem cell procedures of  varying sources and types, we want to educate you on what to look for in a physician who says they perform stem cell procedures.

One of the biggest things that you should look for is experience. You need to look for a doctor who performs a lot of stem cell procedures.

  • At the Magaziner Center for Wellness, Dr. Greenberg can perform 30 stem cell procedure is a month.
  • If you find a doctor who only performed a few stem cell procedures, or a very limited number a month, or is just getting started in the field, you should allow that doctor a lot of time to get some experience under his/her belt.

It’s really worthwhile to go to a doctor who understands procedures such as regenerative prolotherapy injections and regenerative orthopedics. This doctor will understand the bio mechanics of the patient and understand the biology behind stem cells.

These factors, we believe, will give you the best chance at a successful outcome.

An injured joint or spine cannot be treated in isolation or with a single treatment mentality.  This means that if you are at the doctor’s office, and you are being told that a single injection into your shoulder or your hip or knee or other joint, or that a single injection into your neck or low back will be enough, it will likely not be enough. Degenerative joint disease treatment needs a well designed and comprehensive treatment program.

Stem cell therapy can offer long-lasting repair of osteoarthritic knees

Because cortisone and viscosupplementation (hyaluronic acid injections or hyaluronan injections), are given as single injections in varying frequencies, we are often asked, how long do stem cell injections last. Stem cell injections are not cortisone and viscosupplementation, stem cell injections are designed to be long lasting.

Doctors at Chinese Academy of Medical Sciences and China’s Cellular Biomedicine Group found that one of the reasons stems cell therapy is effective is that after a single injection, the new stems cells remained viable and active within the knee for 10 weeks. The doctors also noted that this extended duration stay is required in order for stem cells to exert their functions on promoting joint regeneration and/or cartilage protection.(1). Now this may sound similar to what cortisone or hyaluronic acid injections may do, however, this supports the idea that a comprehensive stem cell treatment program is needed. Because the stem cells stay vital for so long, treatments at intervals become cumulative. Cortisone and hyaluronic acid injections “wear out,” they are not cumulative nor regenerative.

This may help explain why long-term benefit of stem cells are seen in this research:

Doctors at the Department of Orthopedics, Medical College of Shihezi University in China published findings suggested in treated patients stem cell therapy offered long-term relief of symptoms. The doctors were able to conclude their long-term study by saying: “Stem Cell treatment in patients with knee osteoarthritis showed continual efficacy for 24 months compared with their pre-treatment condition.” (2)

In the International journal of rheumatic diseases, doctors found at the end of the five-year follow-up that stem cell treated knees were still better than before treatment.(3)

Stem cell treatment at the Magaziner Center

Stem cell treatments are long-lasting when they are part of a comprehensive treatment program. This video presents a patient of Dr. Scott Greenberg. This woman suffers from bone on bone osteoarthritis. Here you will see a comprehensive treatment as offered by the Magaziner Center for Wellness and Dr. Greenberg. We hope this will allow you to make comparison decisions in how you treat your knee osteoarthritis.

1 Li, M., Luo, X., Lv, X., Liu, V., Zhao, G., Zhang, X., Cao, W., Wang, R., … Wang, W. (2016). In vivo human adipose-derived mesenchymal stem cell tracking after intra-articular delivery in a rat osteoarthritis model. Stem cell research & therapy7(1), 160. doi:10.1186/s13287-016-0420-2

2 Cui G-H, Wang YY, Li C-J, Shi C-H, Wang W-S. Efficacy of mesenchymal stem cells in treating patients with osteoarthritis of the knee: A meta-analysis. Experimental and Therapeutic Medicine. 2016;12(5):3390-3400. doi:10.3892/etm.2016.3791.
3 Davatchi F, Sadeghi Abdollahi B, Mohyeddin M, Nikbin B. Mesenchymal Stem Cell Therapy for knee osteoarthritis: 5 years follow-up of three patients. Int. J. Rheum. Dis. 2015 May 20. doi: 10.1111/1756-185X.12670.