Overactive bladder treatment is more than just a pill - Magaziner

Overactive bladder treatment is more than just a pill

The myriad of urinary problems in both men and women and erectile dysfunction in men are discussed with new research.

Overactive bladder symptoms and urinary incontinence
Metabolic syndrome is a term used to describe a group of conditions that occur together: These are:

  • increased blood pressure,
  • a high blood sugar level,
  • excessive “belly fat” and
  • “bad” cholesterol levels that can increase your risk for heart disease, stroke and diabetes.

The literature on Metabolic Syndrome and Overactive bladder or LUTS (lower urinary tract symptoms) in women is limited, and poor quality.

However, the evidence available on obesity appears to support Metabolic Syndrome as a contributor and predictor of LUTS in women.

Many of the women with LUTS will be overweight and will have features of the Metabolic Syndrome, if looked for. Emphasis on “IF LOOKED FOR.” 

This provides not only an opportunity to encourage weight loss as an adjunct to therapy for overactive bladder symptoms but also a window of opportunity to address cardiovascular risk factors and prevent future cardiovascular morbidity and mortality.1

This new research confirms previous studies suggesting that patients with Metabolic syndrome suffered from overactive bladder symptoms and urinary incontinence and these problems were brought on by abdominal obesity and hyperglycemia.2

Insulin resistance, especially in women, may play significant role in the development of overactive bladder

In another paper, researchers confirmed that metabolic syndrome and obesity have been advocated to be risk factors for the development of overactive bladder. Because, insulin resistance is the underlying mechanism of metabolic syndrome, it should be of no surprise that insulin resistance, especially in women, may play a significant role in the development of overactive bladder.3

Men with large waists urinate more frequently than their slimmer counterparts

Belly fat is a national plague. The myriad of health problems associated with belly fat are so numerous that to mention them all would require you to read a very long list of the obvious. Here is one less well known – the problems of frequent urination.

In a recent published study, men with large waists urinate more frequently than their slimmer counterparts.

  • Researchers from Weill Medical College, Cornell University, New York, found that men with waists measuring 39+ inches reported up to three times more urinary problems than men with waists of 39 inches or less.
  • They also found that larger waist measurements were associated with a greater prevalence of high blood pressure, cardiovascular disease, type 2 diabetes and erection and ejaculation problems.
  • Larger waist circumference was also associated with urinating more than twice during the night – with 44% of men in the largest waist group reporting this, compared with 29% in the middle group and 15% in the smallest waist group.

Men with larger waists were also more likely to report erection problems

Men with larger waists were also more likely to report erection problems than men in the middle and smallest waist groups (74.5%, 50% and 32% respectively) and more likely to report ejaculation problems (65%, 40% and 21% respectively.)

The same pattern was observed for high blood pressure (33.5%, 22% and 14.5% respectively), coronary artery disease (29%, 17% and 8%), type 2 diabetes (33%, 16% and 11%) and cholesterol (254mg/dL, 176 mg/dL and 148 mg/dL).

The researchers also analyzed the relationship between waist size and the odds risk of greater problems from various urological, sexual, metabolic and cardiovascular problems. This showed that:

Men in the largest waist group had a 39% higher odds risk of prostate volume problems than men in the smallest waist group. The odds risk of higher prostate-specific antigen levels was 111% greater and the odds risk of a higher International Prostate Symptom Score was 68%.

The odds risk of erection problems was 132% higher and it was 202% higher for ejaculation problems. High blood pressure, type 2 diabetes and coronary artery disease were 131%, 188% and 250% higher.fore represent an easy diagnostic tool when it comes to the likelihood of male urinary problems.” 4,5

Recently we published articles on the Magaziner Center website discussing belly fat.Here are some highlights:

Researchers writing in the American Journal of Clinical Nutrition say that their findings suggest that calcium and/or vitamin D supplementation contributes to a beneficial reduction of VAT (visceral adipose tissue) or “belly fat.”6

There has been an incredible amount of research published on the obvious. Abdominal fat is the strongest indicator of future and present health risks. Researchers in the medical journal Obesity noted that the best test to determine risk for heart disease, stroke, diabetes, insulin resistance, and other chronic disease was a tape measure to measure your waist.7

Researchers writing in the medical journal Diabetes Care agree. They say while overall body fat and fitness levels are important in predicting health risks, it is your waist size or the measurement of abdominal obesity that is the still the measurement to assess health risk among older adults.8

Weight loss is both complex and simple. The complexities come from not understanding what is best for your body – and this is why diet programs fail. At the Magaziner Center for Wellness we offer many weight loss programs to look at things like low vitamin levels such as vitamin D and calcium and others and test your body chemistry.

1. Tubaro A, Wagg A. Is there a link between overactive bladder and the metabolic syndrome in women? A systematic review of observational studies. Int J Clin Pract. 2015 Feb;69(2):199-217. doi: 10.1111/ijcp.12518. Epub 2014 Dec 11
2. Boudokhane S, Marmouche H, Klii R, Jellad A, Mahjoub S, Ben Salah Frih Z. Urinary disorders and metabolic syndrome: prospective study Prog Urol. 2013 Apr;23(4):256-61. doi:
3. Uzun H, Yilmaz A, Kemik A, Zorba OU, Kalkan M. Association of insulin resistance with overactive bladder in female patients. Int Neurourol J. 2012 Dec;16(4):181-6. doi: 10.5213/inj.2012.16.4.181. Epub 2012 Dec 31.
5. Lee RK, Chung D, Chughtai B, et al. Central obesity as measured by waist circumference is predictive of severity of lower urinary tract symptoms. BJU International, 2012; 110 (4): 540 DOI: 10.1111/j.1464-410X.2011.10819.x
6. Rosenblum JL, Castro VM, Moore CE,et al. Calcium and vitamin D supplementation is associated with decreased abdominal visceral adipose tissue in overweight and obese adults. Am J Clin Nutr January 2012 vol. 95 no. 1 101-108
7. Shen W, Punyanitya M, Chen J, Gallagher D, Albu J, Pi-Sunyer X, Lewis CE, Grunfeld C, Heshka S, Heymsfield SB. Waist Circumference Correlates with Metabolic Syndrome Indicators Better Than Percentage Fat.
8. Racette SB, Evans EM, Weiss EP, Hagberg JM, Holloszy JO. Abdominal Adiposity Is a Stronger Predictor of Insulin Resistance Than Fitness Among 50–95 Year Olds. Diabetes Care 29:673-678, 2006

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